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Nicotinic Acid-Induced Acanthosis Nigricans
Brown-black discoloration and a soft, velvety papillomatosis of the axillary, inguinal, genital, and neck areas were seen in a 46-year-old man. He had hypertriglyceridemia, for which he had recently begun taking nicotinic acid. After a few days of therapy, he noticed the onset of this asymptomatic hyperpigmentation.
Brown-black discoloration and a soft, velvety papillomatosis of the axillary (shown here), inguinal, genital, and neck areas were seen in a 46-year-old man. He had hypertriglyceridemia, for which he had recently begun taking nicotinic acid. After a few days of therapy, he noticed the onset of this asymptomatic hyperpigmentation.
Dr Reynold C. Wong of Sacramento, Calif, made the diagnosis of nicotinic acid–induced acanthosis nigricans and discontinued the patient's medication for hypertriglyceridemia. Three weeks later, the hyperpigmentation and papillomatosis had nearly resolved.
Lebrikizumab Demonstrates Efficacy, Safety in Patients With Skin of Color With AD
June 11th 2025RAD 2025. Lebrikizumab improved skin clearance, itch, and pigmentation in patients with skin of color and atopic dermatitis, with strong safety data through 24 weeks, according to late-breaking data.
