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Lymphangioma Circumscriptum Presenting as Grouped Blisters
A 69-year-old man with a long history of lymphedema secondary to repeated cellulitis sought medical care for mildly pruritic, nontender, purple nodules that had erupted on the bottom and side of one foot 6 months earlier. Scale surrounded the nodules.
A 69-year-old man with a long history of lymphedema secondary to repeated cellulitis sought medical care for mildly pruritic, nontender, purple nodules that had erupted on the bottom and side of one foot 6 months earlier. Scale surrounded the nodules.
Dr Reynold C. Wong of Sacramento, Calif, considered Kaposi sarcoma and lymphangiomas in the differential. Microscopic examination of a biopsy specimen revealed cystically dilated lymph vessels lined with a single layer of endothelium. The vessels contained a mixture of erythrocytes and lymph. These findings confirmed the diagnosis of lymphangiomas secondary to lymphedema.
A large number of lymphangiomas in a localized area, such as this patient's foot, are associated with widespread lymphatic abnormality; therefore, surgical removal of the lesions is not effective therapy. The patient was advised to wear support stockings for the underlying lymphedema.
Lebrikizumab Demonstrates Efficacy, Safety in Patients With Skin of Color With AD
June 11th 2025RAD 2025. Lebrikizumab improved skin clearance, itch, and pigmentation in patients with skin of color and atopic dermatitis, with strong safety data through 24 weeks, according to late-breaking data.
