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Livedo Reticularis: A Classic Presentation
Livedo reticularis is the cutaneous manifestation most frequently associated with the antiphospholipid syndrome (APS). It manifests as a dusky, violaceous vascular discoloration with a reticulated pattern on the upper and lower extremities.
Livedo reticularis (Figure) is the cutaneous manifestation most frequently associated with the antiphospholipid syndrome (APS). It manifests as a dusky, violaceous vascular discoloration with a reticulated pattern on the upper and lower extremities.2
Livedo reticularis is not specific for APS, however, and can occur in other conditions, including connective-tissue diseases and infections, and as a normal variant. Other cutaneous findings in APS include necrotizing vasculitis, livedoid vasculitis, ulcers, thrombophlebitis, cutaneous necrosis and gangrene, and painful skin nodules.2 APS may be managed with aspirin, prednisone, and/or warfarin.
Lebrikizumab Demonstrates Efficacy, Safety in Patients With Skin of Color With AD
June 11th 2025RAD 2025. Lebrikizumab improved skin clearance, itch, and pigmentation in patients with skin of color and atopic dermatitis, with strong safety data through 24 weeks, according to late-breaking data.
