A 56-year-old man, who had a history of cigarette smoking, noticed a sudden swelling in his neck, mainly on the right side. Shortly thereafter, his right arm became enlarged.
A 56-year-old man, who had a history of cigarette smoking, noticed a sudden swelling in his neck, mainly on the right side. Shortly thereafter, his right arm became enlarged.
The patient complained of an uncomfortable sensation of fullness in his head and neck, but no real pain. Superior vena cava syndrome was suspected. A chest film demonstrated a hilar mass, and a CT scan showed venous encroachment with associated thrombus.
This patient had some relief of symptoms with radiotherapy and concomitant heparin, then coumadin, therapy. He died 5 months later from his cancer.
Roche, Alnylam Advance Zilebesiran Into Phase 3 CV Outcomes Trial for Resistant Hypertension
September 9th 2025Zilebesiran’s twice-yearly dosing and sustained BP reductions could offer a new therapeutic approach for adults with resistant hypertension and high CV risk who are uncontrolled on current SOC regimens.
Oral PCSK9 Inhibitor Enlicitide Meets All End Points in Phase 3 Hypercholesterolemia Trial
September 2nd 2025At week 24, patients receiving once-daily enlicitide demonstrated statistically significant and clinically meaningful reductions in low-density lipoprotein cholesterol compared with placebo.