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Heterochromia Iridis
Heterochromia iridis may be inherited or acquired. Acquired heterochromia may be caused by chronic uveitis, or (rarely) an underlying neuroblastoma. Here: a case in point.
A 20-year-old woman is noted to have one blue and one brown iris.
Key point: By definition, this individual demonstrates complete heterochromia iridis. There are varying degrees of this phenomenon, including sectoral and central heterochromia. This finding may be inherited or acquired.
Treatment: Acquired heterochromia may be caused by chronic uveitis, or (rarely) an underlying neuroblastoma. The latter etiologies should be sought and treated accordingly.
Note: Inherited heterochromia may be associated with Waardenburg syndrome (in conjunction with sensorineural deafness) or with piebaldism (in conjunction with a central forelock of white hair).
Atopic Dermatitis: The Pipeline and Clinical Approaches That Could Transform the Standard of Care
September 24th 2025Patient Care tapped the rich trove of research and expert perspectives from the Revolutionizing Atopic Dermatitis 2025 conference to create a snapshot of the AD care of the future.
