- Clinical Technology
- Adult Immunization
- Hepatology
- Pediatric Immunization
- Screening
- Psychiatry
- Allergy
- Women's Health
- Cardiology
- Pediatrics
- Dermatology
- Endocrinology
- Pain Management
- Gastroenterology
- Infectious Disease
- Obesity Medicine
- Rheumatology
- Nephrology
- Neurology
- Pulmonology
Is this hard, pigmented nodule malignant?
Several months earlier, this asymptomatic, pigmented, hard nodule arose on the upper arm of a 37-year-old woman.
Case 1:
Several months earlier, this asymptomatic, pigmented, hard nodule arose on the upper arm of a 37-year-old woman.
Case 1: Dermatofibroma
Lateral compression of the lesion produced a downward dimpling suggestive of a dermatofibroma, D. This often pigmented, benign fibrous nodule can mimic a melanocytic lesion. No treatment is necessary.
Pigmented basal cell carcinomas usually are not hard and bleed easily. Dysplastic nevi are not hard nodules. Desmoplastic melanomas are hard but typically do not dimple downward. Epidermoid cysts are nonpigmented, feel rounded, and reveal a central punctum, which may exude keratinaceous material with pressure.
Atopic Dermatitis: The Pipeline and Clinical Approaches That Could Transform the Standard of Care
September 24th 2025Patient Care tapped the rich trove of research and expert perspectives from the Revolutionizing Atopic Dermatitis 2025 conference to create a snapshot of the AD care of the future.
