In the US, COVID-19 primary series vaccination is recommended for everyone aged 5 years and older, however, vaccine misinformation and hesitancy are still rampant and can touch everyone. Parents and older children may have a host of questions and concerns they want to discuss with their physician regarding COVID-19 vaccination and booster shots. Terry Brenneman, MD, recently sat down with Patient Care Online and shared concerns he has been hearing from patients and how physicians can help educate their patients on COVID-19 vaccination. Dr Brenneman is a pediatrician and founder of North Raleigh Pediatric Group in North Carolina.