Long-standing chorioretinal scarring in both eyes didnot affect a 67-year-old woman’s vision. The scars wereroundish, irregular, and yellowish white with interior pigmentation(A and B).
Long-standing chorioretinal scarring in both eyes didnot affect a 67-year-old woman's vision. The scars wereroundish, irregular, and yellowish white with interior pigmentation(A and B). This patient had presumed ocular histoplasmosissyndrome (POHS), a common disorder in regions such asthe Mississippi, Ohio, and Missouri river valleys, wherethe fungus Histoplasma capsulatum is endemic. Inhaledspores of the culprit organism cause granulomas in thelungs, liver, spleen, and the choroid of the eye. Unless themacula is involved, the patient's vision is unaffected. Typicalfindings in infected patients include:
Macular involvement results in impaired vision. Lasertreatment of macular lesions is ineffective; however, activelesions outside the macula may be treated with laser photocoagulation.Treatment of inactive lesions is not advisedbecause it may stimulate subretinal neovascularization.Because this patient's lesions were inactive, notherapy was warranted. Annual eye examinations wererecommended.
FluMist Intranasal Flu Vaccine Now Available for At-Home Delivery and Self-Administration
August 18th 2025AstraZeneca launches FluMist Home, the first FDA-approved at-home flu vaccine service, allowing self- or caregiver administration of the intranasal influenza vaccine for the 2025–26 season.