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Erythema Multiforme in a Middle-Aged Woman
A 55-year-old woman had a 10-day historyof a nonproductive cough and apainful rash on both palms for 5 days.The eruption subsequently spreadover her entire body.
A 55-year-old woman had a 10-day historyof a nonproductive cough and apainful rash on both palms for 5 days.The eruption subsequently spreadover her entire body.Erythema multiforme--a reactivedermatosis exacerbated by a varietyof stimuli--was diagnosed. Thehive-like rash is more tender thanpruritic and features bull's-eye lesions.The 2 classic infectious causes areherpes simplex virus and Mycoplasmapneumoniae. Further evaluation ofthe patient confirmed the mycoplasmalsource; the infection responded toappropriate antibiotic therapy.The skin eruption improved dramaticallyafter a few days of systemiccorticosteroid therapy. (Case and photograph courtesy of Dr David L. Kaplan.)
FDA Approves Guselkumab for Pediatric Plaque Psoriasis and Active Psoriatic Arthritis
September 30th 2025The FDA has approved guselkumab for children aged 6 years and older with moderate to severe plaque psoriasis or active psoriatic arthritis, making it the first IL-23 inhibitor authorized for pediatric use.
