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Erythema Chronicum Migrans in Lyme Disease
A 34-year-old man experienced fever and arthralgia several days after appearance of the rash.
A 34-year-old man experienced fever and arthralgia several days after appearance of the rash shown here (A). He did not recall being bitten by a tick, as is often the case with persons who contract Lyme disease. The characteristic rash of Lyme disease-an annular red eruption with a central clear area-is observed in fewer than 50% of cases. Variations include an ecchymosis-like rash, such as the one seen here; vesicles; and diffuse erythema.
Macular eruption resulting from Lyme disease is seen in the axilla of a 30-year-old man (B) and on the back of a 71-year-old woman (C).
FDA Approves Guselkumab for Pediatric Plaque Psoriasis and Active Psoriatic Arthritis
September 30th 2025The FDA has approved guselkumab for children aged 6 years and older with moderate to severe plaque psoriasis or active psoriatic arthritis, making it the first IL-23 inhibitor authorized for pediatric use.
