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Dysplastic Polyp in a Woman with UC: What Next?
A medication change? Repeat colonoscopy with chromoendoscopy? Colectomy? Other?
A 46-year-old woman with a long standing history of ulcerative colitis undergoes surveillance colonoscopy. She is managed with oral mesalamine. During the procedure, she is noted to have mild pan colitis. One flat 10-mm polyp is seen. Biopsies of this lesion and surrounding tissue demonstrate dysplasia.
Which of the following would you recommend? Why?
A. Change her medication to an immunomodulator and repeat colonoscopy in 1 year
B. Repeat colonoscopy and perform chromoendoscopy
C. Refer for a colectomy
D. Screen her for primary sclerosing cholangitis
Please leave your answer below, then click here for answer and discusison.
Clinical Tips for Using Antibiotics and Corticosteroids in IBD
January 5th 2013The goals of therapy for patients with inflammatory bowel disorder include inducing and maintaining a steroid-free remission, preventing and treating the complications of the disease, minimizing treatment toxicity, achieving mucosal healing, and enhancing quality of life.
