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Dermatofibrosarcoma Protuberans
This tumor is a low-grade soft tissue sarcoma. Metastases are uncommon, but local recurrence is very frequent. Mohs surgery is the optimal treatment modality.
A 56-year-old man presented for evaluation of an asymptomatic lesion on the right shoulder. This was discovered accidentally while his wife was giving him a massage.
Key point: There was a subtle 3-cm2 area of thickened nodularity on the shoulder. The lesion was better palpated than visualized. A small punch biopsy revealed this to be dermatofibrosarcoma protuberans.
Treatment: The patient’s tumor was removed easily by Mohs micrographic surgery.
Note: This tumor, often referred to as DFSP, is a low-grade soft tissue sarcoma. While metastases are uncommon (5% to 10%), local recurrence is very frequent. Excision with real-time margin control (eg, Mohs surgery) is the optimal treatment modality. An alternative treatment is simple excision with concomitant wide margin removal (5 cm minimum).
Atopic Dermatitis: The Pipeline and Clinical Approaches That Could Transform the Standard of Care
September 24th 2025Patient Care tapped the rich trove of research and expert perspectives from the Revolutionizing Atopic Dermatitis 2025 conference to create a snapshot of the AD care of the future.
