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Benign Blue Nevus
A biopsy is mandatory since the diagnosis includes melanoma. This blue-black macule proved to be a blue nevus.
An 50-year-old woman was concerned about the recent appearance of a small dark spot on the forehead. She denied trauma to the affected area, and was not taking medication.
Key point: The differential diagnosis of a blue-black macule such as this includes both malignant (melanoma) and benign (blue nevus, angioma) tumors, as well as dyschromia from exogenous factors (minocycline administration, traumatic graphite tattoo). A biopsy is mandatory in this case to establish the correct diagnosis.
Treatment: A conservative excisional biopsy (using a 4-mm punch) was done. The lesion proved to be a benign blue nevus.
Note: This type of nevocellular neoplasm appears blue because of the reflective and refractive properties of the considerable dermal melanin that is present. Such lesions only exceptionally transform into malignant tumors.
Atopic Dermatitis: The Pipeline and Clinical Approaches That Could Transform the Standard of Care
September 24th 2025Patient Care tapped the rich trove of research and expert perspectives from the Revolutionizing Atopic Dermatitis 2025 conference to create a snapshot of the AD care of the future.
