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Basal Cell Carcinoma on Face of a 75-Year-Old Woman
A 75-year-old Hispanic woman presented with a slowly growing, asymptomatic facial lesion of about 3 years' duration.
A 75-year-old Hispanic woman presented with a slowly growing, asymptomatic facial lesion of about 3 years' duration.
Physical examination disclosed a 6.5 × 4.5-cm, irregularly shaped plaque that involved both the pinna and preauricular skin. The lesion had a prominent rolled border; multiple discrete, darkly pigmented nodules; and central regression with fibrosis. A biopsy revealed nests of typical basal cell carcinoma with massive deposition of melanin within the tumor cells. The tumor was removed using Mohs microscopic surgery.
Dr Ted Rosen of Houston writes that basal cell carcinoma can sometimes simulate melanoma and manifest unusual coloration on dark-skinned persons.
FOR MORE INFORMATION:
- Kalter DC, Goldberg LH, Rosen T. Darkly pigmented lesions in dark-skinned patients. J Dermatol Surg Oncol. 1984;10:876-881.
Kymera's Oral STAT6 Degrader KT-621 Shows Biologic-Like Activity in Early Atopic Dermatitis Trial
December 8th 2025KT-621 achieved deep STAT6 degradation and strong 4-week EASI and itch reductions, offering a potential new oral option for moderate–severe AD and other Th2 inflammation-driven disease.
