This lesion on her knee had been present for 5 years, reported a 22-year-old woman. It was not related to any trauma; its size had not changed, but occasionally it became darker or lighter. Excisional biopsy revealed lymphangioma circumscriptum, a benign, hamartomatous malformation of dilated lymph channels that may be filled with clear fluid because of communication with deeper lymphatics or, as in this case, serosanguinous fluid.
This lesion on her knee had been present for 5 years, reported a 22-year-old woman. It was not related to any trauma; its size had not changed, but occasionally it became darker or lighter. Excisional biopsy revealed lymphangioma circumscriptum-a benign, hamartomatous malformation of dilated lymph channels that may be filled with clear fluid because of communication with deeper lymphatics or, as in this case, serosanguinous fluid.
Treatment (excisional biopsy) is indicated primarily for diagnosis, cosmetic reasons, and relief of patient anxiety, writes Robert P. Blereau, MD, of Morgan City, La, but it also prevents leakage of fluid and infection. The deep communicating lymphatic cistern must also be excised, otherwise lesions likely will recur.
FluMist Intranasal Flu Vaccine Now Available for At-Home Delivery and Self-Administration
August 18th 2025AstraZeneca launches FluMist Home, the first FDA-approved at-home flu vaccine service, allowing self- or caregiver administration of the intranasal influenza vaccine for the 2025–26 season.