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Atrophie Blanche
A 57-year-old man with a history of venous stasis leg ulceration wondered about the “white spots” on his leg.
A 57-year-old man with a history of venous stasis leg ulceration wondered about the “white spots” on his leg. The condition is atrophie blanche, which manifests as smooth, ivory-white macules and plaques of sclerosis stippled with telangiectasia that often are surrounded by mild to moderate pigmentation.
Atrophie blanche is seen most commonly in association with the healing phase of livedo vasculopathy and hypertensive vasculopathy, but it is noted also as a nonspecific finding in diabetes mellitus, dysproteinemic states, lupus erythematosus, and venous stasis.
Treatment for atrophie blanche is directed at prevention by addressing the underlying medical condition.
Sotagliflozin in Patients with Type 1 Diabetes and CKD to be Discussed at October FDA AdComm Meeting
October 14th 2024Lexicon's sotagliflozin is on the October 31 docket for discussion by the FDA's Endocrinologic and Metabolic Drugs Advisory Committee; PDUFA goal date remains set for December 20.
