Alcohol Use at Any Level Tied to Increased Risk of Dementia: Daily Dose
Your daily dose of the clinical news you may have missed.
Lisa Larkin, MD, on the Importance of Recognizing and Managing Vasomotor Symptoms in Menopause
Women increasingly seek evidence-based menopause care as awareness grows, yet many still suffer from untreated vasomotor symptoms.
Migraine Risk Rises With Unexpectedness of Daily Experiences, the "Surprisal" Factor
Higher surprisal scores, measuring how atypical a daily experience is, increased migraine odds by 86% at 12 hours and 115% at 24 hours in new cohort study.
FDA Accepts sNDA for Roflumilast Cream 0.3% to Treat Plaque Psoriasis in Children Aged 2 to 5 Years
FDA reviews roflumilast cream for young children with plaque psoriasis, potentially offering a first-of-its-kind topical treatment option.
Tralokinumab Looks Promising to Treat Hand Involvement in Atopic Dermatitis
LEO Pharma reveals promising 32-week results for tralokinumab, showing significant benefits for adults with moderate-to-severe hand eczema.
Use of OTC Products and Persistent Vulvovaginal Irritation in Postmenopausal Women, with Caroline Mitchell, MD, MPH
Harvard's Caroline Mitchell, MD, MPH, explains how common OTC products can worsen vulvovaginal symptoms and the importance of a targeted history in GSM care.
AI and Polygenic Risk Scores May Reshape Breast Cancer Screening Within the Decade
Donna Plecha, MD, discusses how AI-powered mammography risk prediction and polygenic risk scores will enable personalized breast cancer screening within the next decade.
Donna Plecha, MD: How to Talk to Women About Dense Breasts and Supplemental Breast Cancer Screening
Breast imaging expert, Donna Plecha, MD, provides a roadmap for primary care physicians to implement risk assessment tools and high-risk clinic referrals in their practice.
Perimenopause Misdiagnosis Affects Nearly 40% of Women as Clinicians Fail to Recognize Hormonal Transition
Nearly 40% of perimenopausal women report misdiagnosis as clinicians treat for anxiety and depression without addressing underlying hormonal imbalance.
High Ultra-Processed Food Intake Linked to Increased Risk of Early-Onset Colorectal Adenomas in Women
New research links high ultra-processed food intake to increased risk of precursors for early-onset colorectal cancer in women under 50.
Hormone Replacement Therapy After the WHI: Clinician’s Evidence Timeline (2002–2025)
The comprehensive timeline highlights how WHI findings and subsequent research reshaped HRT risk assessment, guidance, and FDA labeling through 2025.
Agitation in Alzheimer Disease: What Clinicians Need to Ask, Assess, and Address
A geriatric psychiatrist's clinical pearls on agitation in AD, incluiding behavioral cues, triggers, and evidence-based treatment strategies for primary care.
Weekly Dose Podcast: New Insights on Colonoscopy Adherence, rt-CGM in GDM, Semaglutide Effects, Parent Vaccine Views, and MI Causes
Topics include rideshare support for colonoscopy, rt-CGM benefits in GDM, semaglutide and food noise, vaccine views, and MI etiology.
Multicancer Early Detection Tests Cut Stage IV Diagnoses by Nearly Half Over 10 Years
A 10-year microsimlation model of annual MCED testing revealed signficant reductions in late-stage cancer diagnoses, particularly for cancers lacking routine screening,
Real-World Study Shows Intranasal Epinephrine Effectively Treats Most Allergic Reactions with a Single Dose
Intranasal epinephrine emerges as a promising, needle-free solution for treating severe allergic reactions, showing high effectiveness and usability in clinical settings.
Understanding Alzheimer’s Agitation: Survey Points to Missed Diagnoses and Caregiver Burden
Many caregivers, both paid and unpaid, miss or misinterpret agitation symptoms in Alzheimer disease, fueling stress, stigma, and delayed medical support.
Donna Plecha, MD: The Real Barriers to Optimal Breast Cancer Screening in Women with Dense Breasts
Access, cost, and clinician awareness remain significant barriers to implementing supplemental breast screening, according to Plecha.
Donna Plecha, MD: What PCPs Need to Know About the Dense Breast Notification Law
Breast imaging expert Donna M. Plecha, MD, explains the FDA's dense breast notification requirement and when to recommend supplemental MRI screening.
Initiating Menopausal Hormone Therapy in Primary Care: Where to Start, With Harvard's Caroline Mitchell, MD, MPH
Mitchell highlights hormone therapy prescribing for primary care: treatment algorithms, vaginal estrogen safety, and when progestins aren't needed.
Semaglutide 2.4 mg Improves Liver Health in Patients with MASH, Even at Low Levels of Weight Loss
AASLD 2025: Semaglutide 2.4 mg shows promise in improving liver health in adults with MASH, regardless of weight loss, according to new trial findings.
