Tirzepatide Associated with "Impressive" BP Reduction in Individuals with Obesity
Mean placebo-adjusted SBP change from baseline at 36 weeks was 8.6 mm Hg in adults with obesity, according to authors of the SURMOUNT-1 ABPM substudy.
CDC: Gonorrhea Cases Declined for First Time in Decade, but Syphilis Keeps Climbing
Reported cases of chlamydia, syphilis, and gonorrhea in the US surpassed 2.5 million for the third time in 5 years, according to CDC.
HHS Broadens Access to Medications, Treatment for Opioid Use Disorder
Access to methadone and buprenorphine treatment may be easier and incentive to continue treatment could start at home, using telehealth, according to HHS.
Migraine-Related Stigma Impacts Quality of Life: Daily Dose
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Combination Albuterol/Budesonide Rescue Medication for Adults with Asthma Now Available
The combination SABA/ICS inhaler is the first of its kind and treats both acute bronchoconstriction and the inflammation that drives asthma and disease exacerbation.
Updated Monovalent COVID-19 Vaccines Effective Against Symptomatic Infection, Emerging Variants
The updated COVID-19 vaccines were approximately 54% effective against symptomatic SARS-CoV-2 infection, according to new data from the CDC.
Apixaban Reduced Risk of Stroke in Subclinical Afib Relative to Aspirin but with Greater Risk of Bleeding: ARTRESIA Trial
In apixaban-treated participants, risk of stroke or systemic embolism was reduced by 37%; the risk of disability or fatal stroke declined by 49%, but with noted bleeding risk.
Among Black Women, Hypertension Before Age 30 Years May Triple Risk of Later Stroke
The 3-fold greater risk of subsequent stroke was observed in the Black Women's Health Study's youngest cohort, aged 24-34, investigators reported.
HbA1c Greater than 6.0% Raises T2D Risk in Children with Obesity: Daily Dose
Eating Disorder Hospitalizations Rising among US Adolescents, New Study Warns
Eating disorders among US youth spiked during the COVID-19 pandemic, but a new study shows hospitalizations have been inching up for a decade or more.
Depression Severity Linked to Higher Odds of Asthma, COPD, and Respiratory Symptoms
The risk of cough and asthma in persons with severe depression was 3.32 times and 2.84 times higher, respectively, than that in those without depression, reported researchers.
FDA Announces Plan for Paxlovid Transition from Emergency Use to Approved Labeling
After March 8, 2024, EUA-labeled Paxlovid will no longer be authorized for use, regardless of expiration date, according to the agency.
Use of Cannabis Linked to High Risk of Prevalent Asthma: New Findings
Past month use of cannabis was associated with 43% greater odds of asthma than no use of the drug; odds were 2-fold greater with use of blunts.
Gabapentinoid Use Increasing in US: Daily Dose
Alcohol-Related Liver Disease May be More Deadly Among Women than Men, Study Suggests
Risk of mortality from ALD and MetALD was significantly higher among women even though both phenotypes were more prevalent among men, a new study reveals.
FDA Renews Warning Against Use of Tianeptine-Containing Products, aka “Gas Station Heroin”
Reported adverse events of products with tianeptine include seizures, loss of consciousness, and death, according to the FDA.
Investigational Nonopioid VX-548 Reduces Moderate to Severe Post-Surgical Pain in Late-Stage Clinical Trials
Oral VX-548 has the potential to fill the gap between drugs that are tolerable but lack efficacy and opioids with therapeutic efficacy but known risks, according to Vertex.
Daily Dose: Outpatient C. difficile Underdiagnosed in US
As Measles Outbreak Persists, AAP Urges Clinicians to Ramp Up Infection Control Steps
Measles cases are reported in 6 states, which is not a surprise to one pediatrician who points to the ongoing consequences of falling vaccination rates.
Risk of Preeclampsia, Preterm Birth Prevented as Well by Low-dose Calcium as by Recommended High-Dose, Study Finds
Low-dose calcium supplementation with 500 mg/day may be as protective against poor pregnancy outcomes as the WHO-recommended dose of 1500 mg/day.
