Marla Shapiro, CM, MDCM, on Recognizing Early Perimenopause: Sleep, Mood, and Other Missed Clues
Subtle sleep, mood, and cycle changes may herald perimenopause. Dr. Marla Shapiro discusses how clinicians can recognize and address them early.
Menopause Education Lags in Residency Training Across Primary Care Specialties
Less than one-third of residents in IM, FM, and OB/GYN programs receive structured menopause training, leaving many unprepared for midlife women’s care.
Timing of Menopausal Hormone Therapy May Impact Biomarkers of Alzheimer Disease
A secondary analysis of the ELITE trial suggests that there may be a postmenopausal "critical window" during which use of MHT is optimal.
Menopause Education Wholly Inadequate for Physician Associates, According to New Survey Results
Only 3% of physician associate respondents reported receiving more than 5 hours of menopause-related training during their professional education.
Treating Hot Flashes May Improve Cognitive Symptoms: Study Author Explains the Connection
TMS 2025: Katrina Wugalter, MA, explains why treating vasomotor symptoms may be key to improving cognitive function during menopause.
APOE ε4 and Inflammation Amplify Risk for Memory Decline in Women with Earlier Menopause
Earlier menopause, APOE ε4, and age-related inflammation combine to accelerate memory decline, revealing key factors in women’s Alzheimer disease risk.
Inequities in Menopause Care: How Provider and Patient Factors Combine to Limit Treatment
TMS: Menopause care isn’t one-size-fits-all—and that’s the problem. Wake Forest data reveal deep disparities in who gets treated and how.
Donna Plecha, MD: Why You Should Start Breast Cancer Risk Assessment at Age 25
TMS 2025: Donna Plecha, MD, an expert in breast imaging, discusses essential breast cancer screening recommendations for primary care physicians.
Topline Real-World Data Show Fezolinetant Improves VMS, Sleep, and Work Productivity in Women With Confirmed Menopausal VMS
TMS: New preliminary data show reduction in bothersome VMS as early as week 4, an effect that led to statistically significant improvements across other life domains.
Four Studies Build Evidence for Elinzanetant as a Safe, Effective Nonhormonal Option for Menopausal Vasomotor Symptoms
TMS: New data pooled across clinical trials confirm elinzanetant’s consistent efficacy, safety, and sleep benefits across diverse populations of menopausal women.
Elinzanetant Improves Sleep Through VMS-Independent Mechanisms, According to New Pooled Analysis
TMS: Mediation analysis found that more than half of elinzanetant's sleep benefit occurs independently of nighttime hot flash reduction, challenging VMS-centric models.
Black Women Prescribed Menopausal Hormone Therapy at Significantly Lower Rates Despite More Severe Symptoms, Study Finds
TMS: Black women are up to 36% less likely to receive a prescription for systemic estrogen than White women, despite more acute and persistent VMS, authors said.
Age, Not Menopause Stage, Drives Cortical Volume Reduction in Midlife Women, New Study Suggests
TMS: Findings from a large study presented at TMS 2025 counter previous reports suggesting menopause-specific effects on brain structure at midlife.
New Large-Scale Study Challenges Previous Research on Menopause and Brain Structure
New research presented at TMS 2025 suggests menopause stage does not accelerate brain volume loss—age does. Study author discusses clinical implications for PCPs.
Pooled Safety Analysis Supports Elinzanetant for Vasomotor Symptoms Through 52 Weeks
Analysis of 4 clinical trials, including 3 from the phase 3 OASIS development program, found treatment-emergent AEs comparable between elinzanetant and placebo.
Provider Specialty and Type Drive Divergent Prescribing Patterns for Symptoms of Menopause
TMS 2025: Wide variability in practice patterns suggests a need for standardized education across both specialties and provider types to ensure consistent quality of care.
6 Latent Menopausal Phenotypes Identified by Machine Learning in 10-Year SWAN Follow-Up
TMS 2025: Machine learning uncovered 6 menopausal phenotypes, linking symptom patterns and metabolic risk and potential for personalized treatment strategies.
The Only Predictable Thing About Perimenopause Is Unpredictability, Says Dr Marla Shapiro
TMS 2025. University of Toronto professor Dr Marla Shapiro explains why perimenopause is unpredictable, including age of onset, duration, and symptoms.
Diagnosing DVT: Clinical Pearls for Challenging Presentations
A family medicine physician shares a case of massive PE presenting as syncope and explains the history questions that prevent missed DVT diagnoses in primary care.
Identifying and Managing Vascular Disease in Primary Care: A Q&A With Family Physician Kabiul Haque, MD
Primary care physicians enhance early detection and management of vascular diseases, emphasizing patient history, screening, and strong relationships for better outcomes.
