In People Living with HIV, Switch from Oral ART to Long-Acting Injectable Significantly Improved Adherence, Persistence
IDWeek 2023: In a large cohort of people living with HIV, those switching from oral ART to long acting CAB+RPV were more than 4x as likely to adhere to the regimen.
Adolescents Prefer Combination Meningococcal Vaccine to Separate MenACWY and MenB Administration a New Study Finds
IDWeek 2023: Adolescents expressed a preference for a combination vaccine covering serogroups A, B, C, W, Y of invasive meningococcal disease, reported researchers.
US Meningococcal Vaccination Coverage Has Increased, but Disparities Persist, According to Data Presented at IDWeek 2023
Findings underscore the persistence of disparities in meningococcal vaccination coverage in the US, particularly for vaccination against serogroup B.
IDWeek 2023 Features Leaders Spanning the Specialty's Expertise
IDWeek 2023: Leading physician scientists will headline plenary sessions and named lectureships on topics ranging from antibiotic stewardship to artificial intelligence.
IDWeek 2023, October 11-15: Preview of Topics and Presentations
IDWeek 2023: Imagine an intriguing hot topic in infectious disease and you'll find a session or 2 where you can learn more and then choose the next topic, rinse, and repeat.
Glycemic Screening in Childhood May Predict Diabetes-Related Complications, According to New Data
ADA 2023: Findings from a new study show that higher levels of glycemia in childhood are associated with future microvascular complications, such as nephropathy and retinopathy.
New Data Suggest Higher Doses of Oral Semaglutide Beneficial for Management of Type 2 Diabetes
ADA 2023. Results from PIONEER PLUS trial showed oral semaglutide 25 mg and 50 mg were superior than 14 mg in reducing HbA1c and body weight in adults with T2D.
Triple Agonist Retatrutide Associated with Weight Loss of up to 24% in 48-Week Phase 2 Trial
ADA 2023: Weight loss with the combination GLP-1/GIP/glucagon receptor agonist was as high as 30% in study participants who received the highest dose.
Oral Semaglutide 50 mg May be Effective Option for Obesity Treatment, According to OASIS 1 Study Authors
ADA 2023. Once-daily oral semaglutide 50 mg induced 15.1% weight loss in adults with overweight or obesity without type 2 diabetes vs placebo.
Oral GLP-1 Agonist Orforglipron Leads to ~15% Mean Body Weight Reduction in Adults with Overweight/Obesity
ADA 2023: The investigational oral GLP-1 RA resulted in weight loss comparable to injectable GLP-1 RA formulations and requires no food or water restrictions.
SURMOUNT-2: Tirzepatide Treatment Leads to Average 15% Weight Loss in Adults with T2D, Obesity
ADA 2023: SURMOUNT-2 findings show tirzepatide is associated with greater weight loss in adults with T2D than any other treatment studied to date.
“Triagonist” Therapy for Type 2 Diabetes and Comorbidities to be Previewed at 2023 ADA Scientific Sessions
ADA 2023. Retatrutide, an investigational triple GLP-1/GIP/glucagon agonist, may provide benefits in liver fibrosis and obesity as well as in glycemic control.
Electronic “Nudges” Linking Flu Vaccination to Potential CV Benefits Boosted Uptake in Older Adults in Denmark
ACC 2023. Electronic nudges highlighting the potential cardiovascular benefits of flu vaccination led to a modest uptake in vaccination rates among older adults in Denmark, according to results of the NUDGE-FLU trial.
Ketogenic Diet Associated with Increased Serum Lipids, 2-fold Greater Risk of MACE
ACC2023. Risk for MACE was nearly 7-fold higher in participants on a keto diet whose LDL-C was already high compared with those on a standard diet with LDL-C in a normal range.
Bempedoic Acid May be Effective Alternative for Statin-intolerant Patients, According to Data from CLEAR Outcomes Trial
ACC 2023. In the CLEAR Outcomes trial, bempedoic acid reduced risk for major CV events by 13% compared with placebo in patients who had, or were at high risk for, CVD.
Likelihood of Optimal GDMT for Patients with T2D, ASCVD Increased with Multifaceted Clinic Intervention
ACC2023. For high-risk T2D patients not receiving optimal treatment for hyperlipidemia, hypertension, or hyperglycemia, intensive, multidisciplinary training for clinic staff could shift practice.
Mediterranean Diet Beneficial for Prevention of Heart Disease, Death in Women
ACC 2023. The Mediterranean diet has a beneficial effect on the primary prevention of cardiovascular disease and death in women, according to new analysis.
Advocate for Hypertension Control and Weight Loss to Patients with Obesity, Suggest Authors of New Study
ACC 2023. Results from a 2-decade study showed that all-cause mortality rates were significantly higher in patients with obesity with uncontrolled HTN compared to those without HTN.
Lifelong Bachelor Status Significant Predictor of Death in Men, Not Women, with Heart Failure
ACC 2023. In an analysis of patients with heart failure, never having been married was associated with worse survival compared with having been married.
Insomnia Associated with Significant Risk for MI, Should be Designated a CV Risk Factor
ACC 2023. A large study found increased risk for MI regardless of age and detected particularly heightened risk among women and persons with diabetes who have insomnia.