A biopsy confirmed that the white mucosal discoloration and scattered small erosions were the result of lichen planus. Eradication may be attempted with potent topical steroids or oral steroids.

A 63-year-old man presented with the chief complaint of stinging, burning, and pain in his mouth. These symptoms were worsened by eating fruit or drinking carbonated beverages.
Key point: Areas of white mucosal discoloration were found throughout the gingival surfaces and the undersurface of the tongue. Scattered small erosions were also present. A biopsy of a 2-mm specimen confirmed the suspected diagnosis of oral lichen planus and excluded leukoplakia.
Treatment: Application of potent topical corticosteroids or administration of oral corticosteroids, is indicated. Unresponsive patients may require oral cyclosporine (2 to 4 mg/kg/d).
Note: The reason to attempt eradication is the small, but real, risk of evolution into cutaneous squamous cell carcinoma. The patient should avoid acidic foods, thereby reducing symptoms.
Atopic Dermatitis: The Pipeline and Clinical Approaches That Could Transform the Standard of Care
September 24th 2025Patient Care tapped the rich trove of research and expert perspectives from the Revolutionizing Atopic Dermatitis 2025 conference to create a snapshot of the AD care of the future.